Reprogramming Efficiency Improvement Service


As revolutionary biotechnology, cell reprogramming provides a powerful tool for designing cell fate and function. iPSCs obtained by reprogramming technology and tissue stem cells or tissue cells obtained by lineage reprogramming technology have great clinical applications and have been successfully used in disease modeling, drug discovery, regenerative medicine, and other fields. However, the inefficiency and safety issues of reprogramming have been the bottleneck of their clinical applications.

In recent years, intensive research has been conducted on how to optimize reprogramming methods. Advances in biomaterials and micro/nanotechnology have led to new breakthroughs in improving reprogramming efficiency and quality. Creative Bioarray has combined micro/nanotechnology-engineered biomaterials and cell reprogramming to develop a variety of strategies to improve reprogramming performance in vitro and in vivo. Our researchers have focused on developing delivery strategies, controlling biophysical and biochemical cues, and improving the reproducibility of reprogramming to achieve efficient cellular reprogramming.

Some strategies in improving the reprogramming efficiency and safety.Fig.1 Some strategies in improving the reprogramming efficiency and safety. (Nakhaei-Rad, 2012)


In order to provide reprogramming services to the satisfaction of our customers worldwide, our researchers have developed several viable strategies to improve the efficiency of cell reprogramming.

  • Development of Reprogramming Delivery Systems
  • To improve reprogramming efficiency and safety, our researchers have developed various delivery systems for reprogramming factors including biological, physical and chemical delivery systems.

  • Biophysical and Biochemical Regulation for Cell Reprogramming
  • We have developed multiple strategies to improve cell reprogramming efficiency based on biophysical and biochemical modulation of cell reprogramming including micro/nanotopography, stiffness, extracellular force stimulation, 3D microenvironment and biochemical modifications.

  • iPSC Reprogramming Reproducibility Improvement Service
  • We have developed several strategies to help our customers improve the reproducibility of iPSC reprogramming based on multiple factors affecting the derivation of iPSCs and their stability and differentiation.

Service Purpose

  • We provide excellent service to our clients through effective collaboration, communication and efforts of our team members.
  • We focus on every client. Our team members take each client's project seriously to develop long-term committed partners.


  • Industry-leading research team and advanced cell reprogramming technology.
  • Scalable platform and flexible, iterative solutions to meet specific customer research needs.
  • Highly specialized scientific experts to help develop cost-effective and landmark projects.

Creative Bioarray provides reliable and professional technical support to our customers in developing strategies to improve the efficiency of cell reprogramming. Our innovative technologies coupled with state-of-the-art laboratory equipment allow us to handle your project efficiently and with reasonable savings in your project costs and time. If you need technical support on cell reprogramming, please contact us directly for further inquiries.


  1. Nakhaei-Rad, S.; et al. New windows to enhance direct reprogramming of somatic cells towards induced pluripotent stem cells. Biochemistry and Cell Biology. 2012, 90(2): 115-123.
For Research Use Only. Not For Clinical Use.